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Your Global Solution Partner Garanti Kimya

Garanti Kimya: Every company is different and demands different solutions. We understand company demands before explaining our products.

With a rich history spanning a decade, Garanti Kimya stands as a testament to dedication, expertise, and unwavering commitment to excellence. As a premier provider of chemical solutions, we specialize in serving the food, pharmaceutical, and cosmetic industries with unmatched precision and efficacy. Diverse Expertise: Our extensive experience has honed our proficiency in a broad spectrum of chemical products, enabling us to cater to the unique and evolving needs of our clients. We understand that the food, pharmaceutical, and cosmetic sectors demand the highest quality and safety standards, and we have a proven track record of meeting and exceeding these expectations.

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Featured Acticle

Fisetin is a senotherapeutic that extends health and lifespan

Source:https://pmc.ncbi.nlm.nih.gov/articles/PMC12899922/
By: Matthew J Yousefzadeh a,1, Yi Zhu b,1, Sara J McGowan a,1, Luise Angelini a,1, Heike Fuhrmann-Stroissnigg a, Ming Xu b, Yuan Yuan Ling a, Kendra I Melos a, Tamar Pirtskhalava b, Christina L Inman b, Collin McGuckian a, Erin A Wade a, Jonathon I Kato a, Diego Grassi a, Mark Wentworth c, Christin E Burd d, Edgar A Arriaga e, Warren L Ladiges f, Tamara Tchkonia b, James L Kirkland b, Paul D Robbins a,⁎, Laura J Niedernhofer a,⁎


Abstract

Background Senescence is a tumor suppressor mechanism activated in stressed cells to prevent replication of damaged DNA. Senescent cells have been demonstrated to play a causal role in driving aging and age-related diseases using genetic and pharmacologic approaches. We previously demonstrated that the combination of dasatinib and the flavonoid quercetin is a potent senolytic improving numerous age-related conditions including frailty, osteoporosis and cardiovascular disease. The goal of this study was to identify flavonoids with more potent senolytic activity.

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